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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARFGAP3 All Species: 15.76
Human Site: S319 Identified Species: 38.52
UniProt: Q9NP61 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NP61 NP_001135765.1 516 56928 S319 C R S V I S H S V T S D M Q T
Chimpanzee Pan troglodytes XP_001171224 516 56901 S319 C R S G I S H S V T S D M Q T
Rhesus Macaque Macaca mulatta XP_001107803 516 56806 S319 C R S G I S H S V T S D M Q T
Dog Lupus familis XP_848847 517 57143 S320 C R S G I S H S V T S D M Q T
Cat Felis silvestris
Mouse Mus musculus Q9D8S3 523 57437 T326 S V T S D M Q T I E Q E S P T
Rat Rattus norvegicus Q4KLN7 525 57652 I328 V T S D M Q T I E Q E S P T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512573 489 53316 T294 S V M T D M Q T I E Q E T P V
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001032507 536 58567 E338 M A E M L V I E Q E T P V G V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09531 529 57893 K331 A G G I R S I K Q D D V L T F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82171 395 43079 T201 G L G A R K L T T K S S G T L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 96.7 88.7 N.A. 80.5 80.3 N.A. 62 N.A. N.A. 56.5 N.A. N.A. N.A. 35.1 N.A.
Protein Similarity: 100 96.3 98.2 94.1 N.A. 88.9 87.8 N.A. 73.8 N.A. N.A. 71 N.A. N.A. N.A. 54.6 N.A.
P-Site Identity: 100 93.3 93.3 93.3 N.A. 6.6 6.6 N.A. 0 N.A. N.A. 0 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 33.3 13.3 N.A. 20 N.A. N.A. 26.6 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 20 0 0 0 0 10 10 40 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 10 10 30 10 20 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 10 10 20 30 0 0 0 0 0 0 0 0 10 10 0 % G
% His: 0 0 0 0 0 0 40 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 40 0 20 10 20 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 10 0 10 0 0 0 0 0 % K
% Leu: 0 10 0 0 10 0 10 0 0 0 0 0 10 0 20 % L
% Met: 10 0 10 10 10 20 0 0 0 0 0 0 40 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 10 20 0 % P
% Gln: 0 0 0 0 0 10 20 0 20 10 20 0 0 40 0 % Q
% Arg: 0 40 0 0 20 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 20 0 50 10 0 50 0 40 0 0 50 20 10 0 0 % S
% Thr: 0 10 10 10 0 0 10 30 10 40 10 0 10 30 50 % T
% Val: 10 20 0 10 0 10 0 0 40 0 0 10 10 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _